State Substitution Laws and Uptake of an Interchangeable Insulin Biosimilar.

ABSTRACT:

Importance

Although biosimilars have potential to reduce drug spending, their use remains low. Automatic substitutions of biologic drugs by their biosimilars at pharmacies can facilitate biosimilar uptake. Yet, state regulations limiting the types and circumstances under which biosimilars may be substituted could discourage efficient biosimilar adoption.

Objective

To examine associations of state substitution laws in the US with biosimilar adoption in the insulin glargine market, in which an interchangeable biosimilar was recently launched.

Design, setting, and participants

This retrospective cohort study using MarketScan commercial claims data examined fills for insulin glargine among users who were younger than 65 years and had fills for the insulin glargine Lantus

SUBMITTER: Kwon Y 

PROVIDER: S-EPMC11971668 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature