Factors associated with declining cytoreductive surgery in advanced epithelial ovarian cancer: a population-based study.

ABSTRACT:

Objective

Cytoreductive surgery serves as a cornerstone intervention for advanced epithelial ovarian cancer (EOC), yet some patients decline the procedure despite clinical recommendations. This study aimed to evaluate survival outcomes and identify sociodemographic and clinical factors associated with this decision in advanced EOC patients.

Methods

A retrospective analysis of EOC cases from the Surveillance, Epidemiology, and End Results (SEER) database (2004-2021) was conducted, including patients with stage III/IV EOC recommended for surgery. Patients were categorized into surgical and non-surgical cohorts. Propensity Score Matching (PSM) was applied to adjust for baseline differences, and survival outcomes were compared using Kaplan-Meier and Cox proportional hazards mode

SUBMITTER: Zhao L 

PROVIDER: S-EPMC11971787 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature