A case for myoglobin-macromolecular rate theory applied to pseudo peroxidase kinetics.

ABSTRACT: This study explores the well-known catalytic behavior of myoglobin as a pseudo-peroxidase by applying macromolecular rate theory (MMRT) to assess its temperature-dependent enzyme kinetics. While myoglobin is primarily recognized for its oxygen-binding properties in muscle tissues, with a characterized pseudo-peroxidase ability to catalyze the degradation of hydrogen peroxide in the presence of electron donors, the claim that myoglobin is actually a true peroxidase can be explored by analyzing the heat capacity changes (ΔC_p ^‡) in the catalyzed reaction at different temperatures and fitting the results to the expanded Eyring equation (MMRT equation). This research uses the MMRT equation to compare myoglobin's catalytic activity (a pseudo-peroxidase) with that of lactope

SUBMITTER: Tuttle C 

PROVIDER: S-EPMC11971986 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature