Patient-specific mapping of fundus photographs to three-dimensional ocular imaging.

ABSTRACT:

Background

Ocular proton beam therapy (OPT) planning would benefit from an accurate incorporation of fundus photographs, as various intra-ocular structures, such as the fovea, are not visible on conventional modalities such as Magnetic Resonance Imaging (MRI). However, the use of fundus photographs in OPT is limited, as the eye's optics induce a nonuniform patient-specific deformation to the images.

Purpose

To develop a method to accurately map fundus photographs to three-dimensional images.

Methods

Personalized optical raytracing simulations were performed for 27 subjects, using subject-specific eye models based on corneal topography, biometry, and MRI. Light rays were traced through the eye for angles of 0°-85° with respect to the optical axis, in steps of 5°. These

SUBMITTER: Haasjes C 

PROVIDER: S-EPMC11972038 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature