Detection of an internal density change in an anthropomorphic head phantom via tracking of charged nuclear fragments in carbon-ion radiotherapy.

ABSTRACT:

Background

Carbon-ion radiotherapy provides steep dose gradients that allow the simultaneous application of high tumor doses as well as the sparing of healthy tissue and radio-sensitive organs. However, even small anatomical changes may have a severe impact on the dose distribution because of the finite range of ion beams.

Purpose

An in-vivo monitoring method based on secondary-ion emission could potentially provide feedback about the patient anatomy and thus the treatment quality. This work aims to prove that a clinically relevant anatomical change in an anthropomorphic head phantom may be detected via charged-fragment tracking during a treatment fraction.

Methods

A clinically representative carbon-ion treatment plan was created for a skull-base tumor in an anthropom

SUBMITTER: Schweins L 

PROVIDER: S-EPMC11972041 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature