No Increased Risk of Hepatitis B Virus Infection in Patients with Celiac Disease: A Population-Based Study.

ABSTRACT:

Objectives

Celiac disease (CeD) has been associated with a low response to hepatitis B (HBV) vaccination, but guidelines for testing and revaccination among individuals with CeD are sparse. We examined the risk of future HBV among individuals with CeD in a population-based Swedish cohort. Furthermore, we examined the rate of prior HBV infection in CeD patients.

Methods

All individuals in Sweden diagnosed with biopsy-verified CeD between 1990 and 2017 were identified through the ESPRESSO cohort. Each individual with CeD was matched by age, sex, calendar year, and birth country (Nordic vs. other) with up to 5 reference individuals.

Results

We identified 44,721 CeD and 222,238 reference individuals. The incidence rates of diagnosed HBV were 2.3 and 2.9 per 100,000 person

SUBMITTER: Jossen J 

PROVIDER: S-EPMC11972206 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature