Trends in cancer mortality under age 50 in 15 upper-middle and high-income countries.

ABSTRACT:

Background

Rising cancer incidence, particularly for colorectal cancer, has been reported in young adults. This study examined whether this is related to an increase in mortality.

Methods

We analyzed World Health Organization mortality data among young adults aged 25-49 years in 15 most populous upper-middle and high-income countries from 1990 to 2021 with reliable data. Midyear populations were retrieved from the United Nations for the American Countries and from the World Health Organization for the other countries. We compared age-standardized mortality rates in 2019-2021 with those in 2009-2011 and performed joinpoint regression analysis for all cancers and selected most common cancer sites: colorectum, pancreas, lung, and breast.

Results

In 2019-2021, the highest

SUBMITTER: Santucci C 

PROVIDER: S-EPMC11972687 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature