Biological and Pharmacological Enhancement of Regeneration in Chronic Spinal Cord Injury.

ABSTRACT:

Study design

Prospective, randomized, single-blind, comparative study.

Primary objective

To compare the efficacy of multiple bone marrow implantations and co-administration of citicoline to multiple bone marrow implantations alone in the treatment of chronic Spinal Cord Injury (SCI).

Setting

The study was conducted at Fathima Matha Physiotherapy and Rehabilitation Center in Kottayam, India.

Methods

Twenty-three participants with chronic traumatic SCI, classified as American Spinal Injury Association Impairment Scale (AIS) A, B, or C, were recruited and randomized into two groups. The first group (BMCT group) received multiple intrathecal implantations of autologous non-manipulated bone marrow aspirate along with oral citicoline (Cytidine Diphosphate Choline). T

SUBMITTER: John PS 

PROVIDER: S-EPMC11972996 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature