L-shaped correlation between serum alpha-1-acid glycoprotein concentration and urinary albumin creatinine ratio in females: a cross-sectional survey.

ABSTRACT:

Background

Alpha-1-acid glycoprotein (AGP) is a vital acute phase reactant that increases when glomerular filtration is impaired, making it a potential biomarker of kidney disease. The urine albumin-to-creatinine ratio (UACR) is a sensitive indicator of proteinuria and is frequently used to screen for kidney disease in its early stage. The aim of this study was to explore their correlation in order to advance our understanding of the mechanisms underlying kidney damage.

Methods

This study included 2579 female participants with serum AGP and UACR from the National Health and Nutrition Examination Survey (2015-2018). We divided all participants equally into three groups based on their serum AGP concentration. The univariate and multivariate regression models were for assessing

SUBMITTER: Wang J 

PROVIDER: S-EPMC11973102 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature