Hypertension Exacerbates Endothelial Dysfunction in Patients With Atrial Fibrillation.

ABSTRACT: Atrial fibrillation (AF) and hypertension (HT) often coincide and both are independently associated with endothelial dysfunction. We tested the hypothesis that brachial artery flow-mediated dilation (FMD), an indicator of endothelial health, will be poorer in AF patients with HT (AF + HT) than AF without concurrent HT. In a cross-sectional design study, AF (n = 29; mean 70 years; 9 females) and AF + HT (n = 33; 68 years (p = 0.302); 14 females) patients underwent Duplex-Doppler ultrasound imaging of brachial artery diameter and flow velocity during baseline (2 min), distal tourniquet cuff inflation (5 min), and following cuff deflation (3 min). The peak increase in artery diameter following cuff deflation was taken as FMD and analyzed as absolute, percentage change, FMD and shear-rate area

SUBMITTER: Thomas S 

PROVIDER: S-EPMC11973128 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature