TASTY trial: protocol for a study on the triad of nutrition, intestinal microbiota and rheumatoid arthritis.

ABSTRACT:

Background

The gut microbiota has been implicated in the onset and progression of Rheumatoid Arthritis (RA). It has been proposed that gut dysbiosis impairs gut barrier function, leading to alterations in mucosal integrity and immunity. This disruption allows bacterial translocation, contributing to the perpetuation of the inflammatory process. Since diet is recognised as a key environmental factor influencing the gut microbiota, nutritional interventions targeting RA activity are currently being explored. This study aims to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet +) can impact the gut microbiota, intestinal permeability, and RA-related outcomes.

Methods

One hundred RA patients are being recruite

SUBMITTER: Charneca S 

PROVIDER: S-EPMC11974026 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature