Critical analysis of macular hole repair techniques: a comprehensive systematic review and meta-analysis comparing internal limiting membrane flap and internal limiting membrane peeling for any size of macular hole.

ABSTRACT:

Background

Macular holes (MHs) are a leading cause of visual impairment and blindness worldwide defined as a partial or full thickness anatomical defect in the fovea of the retina. ILM peeling is an effective surgical procedure to repair the defect. However, this approach lacks efficacy for larger macular holes. ILM flap is a novel technique with demonstrated efficacy for repair of larger defects.

Objective

This systematic review and meta-analysis aims to compare the effectiveness of these two techniques in treating any size and type of MH.

Methods

A comprehensive literature search was conducted in the PubMed, Medline, and Cochrane Library databases to identify the relevant articles. The primary outcome measures were MH closure rate and postoperative VA. The statistic

SUBMITTER: Akhtar SMM 

PROVIDER: S-EPMC11974160 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature