Gut microbiome in patients with early-stage and late-stage endometriosis.

ABSTRACT:

Background

Endometriosis is a chronic inflammatory gynecological disease. Previous studies have explored relationships between endometriosis and the microbiota, but none have focused on differences in gut microbiota between early-stage and late-stage endometriosis patients or their connections to dysmenorrhea symptoms. This study compared gut microbiota compositions between early-stage and late-stage endometriosis patients using amplicon sequencing and further analyzed their dysmenorrhea symptoms.

Methods

To minimize seasonal and dietary impacts, we recruited Guangdong residents hospitalized for surgery at Zhujiang Hospital. Participants underwent preoperative screening based on enrollment criteria and fecal samples were collected. Endometriosis was classified according to t

SUBMITTER: Cai Z 

PROVIDER: S-EPMC11974225 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature