Microbiome and bladder cancer: the role of probiotics in treatment.

ABSTRACT: Bladder cancer (BCa) remains a significant global health challenge, with increasing interest in the role of the bladder microbiome in its pathogenesis, progression and treatment outcomes. The complex relationship between bladder cancer and the microbiome, as well as the potential impact of probiotics on treatment effectiveness, is currently under investigation. Research suggests that the microbiota may influence BCa recurrence prevention and enhance the efficacy of the Bacillus Calmette-Guérin (BCG) vaccine. Recent studies reveal differences in the bladder microbiome between individuals without bladder cancer and those with the disease. In the healthy bladder, Streptococcus and Lactobacillus are consistently identified as the most prevalent genera. However, in men, the predom

SUBMITTER: Dadgar-Zankbar L 

PROVIDER: S-EPMC11974345 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature