On variability in local field potentials.

ABSTRACT: Neuronal coding and decoding would be compromised if neuronal responses were highly variable. Intriguingly, neuronal spike counts (SCs) show a reduction in across-trial variance (ATV) in response to sensory stimulation, when SC variance is normalized by SC mean, that is, when using the Fano factor ¹ . Inspired by this seminal finding, ATV has also been studied in electroencephalography (EEG) signals, revealing effects of various stimulus and cognitive factors as well as disease states. Here, we empirically show that outside of evoked potentials, the ATV of the EEG or local field potential (LFP) is very highly correlated to the intra-trial variance (ITV), which corresponds to the well-known power metric. We propose that the LFP power, rather than the raw LFP signal, should be con

SUBMITTER: Parto-Dezfouli M 

PROVIDER: S-EPMC11974936 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature