Multilevel mortality risk factors among pediatric hematology-oncology patients with deterioration.

ABSTRACT:

Background

Hospitalized pediatric hematology-oncology patients have frequent clinical deterioration events (CDEs) requiring intensive care unit (ICU) interventions and resulting in high mortality, particularly in resource-limited settings. This study identifies independent risk factors for CDE mortality in hospitals providing childhood cancer care in Latin America and Spain.

Methods

Centers implemented a prospective CDE registry, defined as unplanned transfer to a higher level of care, use of ICU-level interventions on the ward, or nonpalliative ward death. The authors analyzed registry data from April 2017 to December 2022. The primary outcome was CDEs mortality, defined as death occurring during ICU admission, <24 hours of ICU discharge, or end of ward-based ICU interventi

SUBMITTER: Agulnik A 

PROVIDER: S-EPMC11975202 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature