Plasma proteins and persistent postsurgical pelvic pain among adolescents and young adults with endometriosis.

ABSTRACT:

Background

Noninvasive biomarkers that predict surgical treatment response would inform personalized treatments and provide insight into potential biologic pathways underlying endometriosis-associated pain and symptom progression.

Objective

To use plasma proteins in relation to the persistence of pelvic pain following laparoscopic surgery in predominantly adolescents and young adults with endometriosis using a multiplex aptamer-based proteomics biomarker discovery platform.

Study design

We conducted a prospective analysis including 142 participants with laparoscopically-confirmed endometriosis from the Women's Health Study: From Adolescence to Adulthood observational longitudinal cohort with study enrollment from 2012-2018. Biologic samples and patient data were colle

SUBMITTER: Sasamoto N 

PROVIDER: S-EPMC11975416 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature