Association Between Triglyceride-Glucose Index and Breast Cancer: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background and aims

The triglyceride-glucose (TyG) index, a surrogate marker for insulin resistance and metabolic syndrome, has been implicated in breast cancer (BC) risk. However, its predictive value remains controversial. This systematic review and meta-analysis assessed the association between the TyG index and BC risk, its role in differentiating malignant from benign breast lesions, and its potential prognostic significance.

Methods

A comprehensive search of PubMed, Scopus, Web of Science, Embase, and Google Scholar was conducted up to January 2025. Studies were included if they met the following criteria: (1) assessed the TyG index about BC risk, progression, or prognosis; (2) included a comparator group (healthy individuals, benign breast lesion patients, or internal

SUBMITTER: Zooravar D 

PROVIDER: S-EPMC11976027 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature