Sex Differences in Achieved Diastolic Blood Pressure and Cardiovascular Outcomes in Elderly Patients With Hypertension.

ABSTRACT:

Background

Blood pressure profiles differ in males and females. Low diastolic blood pressure (DBP) is associated with increased risk of cardiovascular disease (CVD). However, sex differences in achieved DBP and associated CVD risk remain unclear.

Objectives

The aim of this study was to examine sex differences in achieved DBP and CVD outcomes in elderly hypertensive patients.

Methods

This study is a secondary analysis of the STEP (Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients) trial. The mean achieved DBP was compared between male and female participants. The association between mean achieved DBP and cardiovascular risk was evaluated as a continuous and categorical variable with a cubic spline model or Cox proportional hazards regression

SUBMITTER: Ling Q 

PROVIDER: S-EPMC11976241 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature