Quality of life and kidney function in CKD patients: a longitudinal study.

ABSTRACT:

Background

In chronic kidney disease (CKD), a declining glomerular filtration rate (GFR) leads to physiological and psychosocial burdens that impair quality of life (QoL). However, this relationship has been mainly investigated in cross-sectional studies and a limited number of longitudinal studies that reported contrasting results.

Objective and methods

This longitudinal study included 582 patients with Stages 2-5 CKD. QoL was assessed using the Kidney Disease Quality of Life (KDQOL™) instrument at baseline and annually for 3 years. GFR was estimated using the MDRD equation, the equation recommended by guidelines that were contemporary to the study cohort. We analysed the relationship between repeated measures of QoL and GFR using unadjusted and adjusted mixed linear models

SUBMITTER: D'Arrigo G 

PROVIDER: S-EPMC11976526 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature