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Effects of Different Self-Adhesive Resin Cements and Curing Through Zirconia on Gingival Fibroblasts.


ABSTRACT:

Introduction

Self-adhesive resin cements (SARCs) are widely used for fixed prostheses. These cements and their eluted products may affect periodontal tissues. This study aimed to investigate the response of human gingival fibroblasts (HGFs) to eluates from SARCs in vitro, simulating clinical conditions after prosthesis fixation, to gain insights into their potential effects on gingival health.

Methods

Two SARCs, RelyX U200 (RX) and Maxcem Elite Chroma (MC), were polymerised according to the manufacturer's protocols using various curing methods (light-cured, light-cured through 1- or 2 mm zirconia, and self-cured). HGFs were exposed to cement eluates at different concentrations. Cell viability, vitality, wound healing, and gene expression were assessed at different time point

SUBMITTER: Termteerapornpimol K 

PROVIDER: S-EPMC11976558 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature