Association of 41 Inflammatory Cytokines With Common Oral Diseases.

ABSTRACT:

Background

While observational studies have demonstrated a potential link between inflammatory cytokines and oral diseases, the question of causality is warranting further investigation. This study aimed to comprehensively assess the potential causal role of 41 inflammatory cytokines in common oral diseases.

Methods

A two-sample Mendelian randomization (MR) study was conducted using the summary statistics from the largest publicly available genome-wide association study (GWAS) for 41 inflammatory cytokines and common oral diseases (indicated by the index of decayed and filled tooth surfaces divided by number of tooth surfaces (DFSS), index of decayed, missing and filled tooth surfaces (DMFS), number of natural teeth, and periodontitis). Inverse variance weighted regression (

SUBMITTER: Liu Z 

PROVIDER: S-EPMC11976602 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature