Prognostic Value of Nevus-Associated Melanoma in Patients with Melanoma.

ABSTRACT:

Background

Although most melanomas develop de novo, about 30% are nevus-associated melanomas, where the prognostic value is unclear. Our study aimed to determine whether nevus-associated melanoma is associated with sentinel lymph node (SLN) status and prognosis in patients with melanoma.

Methods

The Sentinel Lymph Node Working Group database, which includes comprehensive clinicopathological and outcome data, was utilized to investigate the association of nevus-associated melanoma with SLN status as well as relapse-free (RFS), melanoma-specific (MSS), and overall survival (OS) using multivariable logistic regression and Cox regression modeling.

Results

A total of 3447 adult patients with a median follow-up of 2.6 years (interquartile range 0.9-6.9) were evaluable. Comp

SUBMITTER: Riaz N 

PROVIDER: S-EPMC11976787 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature