Antiviral effect of Bromelain combined with acetylcysteine against SARS-CoV-2 Omicron variant.

ABSTRACT: The recent pandemic represented one of the biggest challenges of modern civilization. SARS-CoV-2 remains an imminent public health threat and currently, there is no effective and greatly affordable treatment for severe COVID-19. Although standard management with dexamethasone, and physical management including physiotherapy, prone positioning and mechanical ventilation are used, severe disease patients may still succumb to infection. In this regard, BromAc^® is a combination therapy of a refined protein derived from Bromelain and acetylcysteine, that shows significant mucolytic and anti-inflammatory properties. In the present study, we performed in vitro, and ex vivo analyses to assess the effect of BromAc^® in inhibiting Omicron variant of SARS-CoV-2 at different level

SUBMITTER: Reis EVS 

PROVIDER: S-EPMC11976912 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature