Respiratory Related Hospitalization in Children With Exposure to Meconium Aspiration or Staining.

ABSTRACT:

Background

We investigated whether neonates exposed to meconium had a higher risk of respiratory hospitalization in childhood.

Methods

We analyzed a longitudinal cohort of 1,271,563 children with 6,334,857 person-years of follow-up between birth and age 5 years in Quebec, Canada from 2006 to 2022. The exposure was meconium aspiration or meconium staining without aspiration at birth. The outcome was hospitalization for bronchiolitis, asthma, and other allergic conditions up to age 5 years. We estimated hazard ratios (HR) and 95% confidence intervals (CI) for the association between meconium exposure and these outcomes using Cox regression models adjusted for patient characteristics. We additionally examined associations according to gestational age.

Results

A total of

SUBMITTER: Cote-Corriveau G 

PROVIDER: S-EPMC11977039 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature