Reduced Pulmonary Artery Distensibility Predicts Persistent Pulmonary Hypertension and 2-Year Mortality in Patients with Severe Aortic Stenosis Undergoing TAVR.

ABSTRACT:

Rationale and objectives

Post-TAVR persistent pulmonary hypertension (PH) is a better predictor of poor outcome than pre-TAVR PH. In this longitudinal study we sought to evaluate whether pulmonary artery (distensibility (D_PA) measured on preprocedural ECG-gated CTA is associated with persistent-PH and 2-year mortality after TAVR.

Materials and methods

Three hundred and thirty-six patients undergoing TAVR between July 2012 and March 2016 were retrospectively included and followed for all-cause mortality until November 2017. All patients underwent retrospectively ECG-gated CTA prior to TAVR. Main pulmonary artery (MPA) area was measured in systole and in diastole. D_PA was calculated as: [(area-MPA_max-area-MPA_min)/area-MPA_max

SUBMITTER: Turner V 

PROVIDER: S-EPMC11977500 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature