Feasibility and Efficacy of Sentinel Lymph Node Mapping in Gastric Cancer.

ABSTRACT:

Background

Lymph node metastasis is a critical prognostic factor for patients with gastric carcinoma (GC). Sentinel lymph node (SLN) mapping has the potential to identify the initial site of draining lymph node metastasis and reduce the extent of surgical lymphadenectomy. This study aimed to evaluate the diagnostic accuracy of SLN mapping in GC.

Methods

The study enrolled 129 GC patients undergoing total or partial gastrectomy with D2 lymphadenectomy and indocyanine green fluorescence-guided SLN mapping. The primary outcomes were the negative predictive value (NPV) and sensitivity of SLN mapping. The secondary outcomes were clinicopathologic factors associated with SLN mapping accuracy and successful SLN mapping.

Results

The SLN detection rate in this study was 86.8 %

SUBMITTER: Abate M 

PROVIDER: S-EPMC11977517 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature