Physical activity-induced alterations of the gut microbiota are BMI dependent.

ABSTRACT: Physical inactivity is one of the leading causes of chronic metabolic disease including obesity. Increasing physical activity (PA) has been shown to improve cardiometabolic and musculoskeletal health and to be associated with a distinct gut microbiota composition in trained athletes. However, the impact of PA on the gut microbiota is inconclusive for individuals performing PA in their day-to-day life. This study examined the role of PA and hand-grip strength on gut microbiome composition in middle-aged adults (40-65 years, n = 350) with normal (18.5-24.9 kg/m² ) and overweight (25-29.9 kg/m² ) body mass index (BMI). PA was recorded using the International Physical Activity Questionnaire, and hand-grip strength was measured using a dynamometer. Serum samples were asses

SUBMITTER: Shah S 

PROVIDER: S-EPMC11977523 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature