Role of Lugol solution before total thyroidectomy for Graves' disease: randomized clinical trial.

ABSTRACT:

Background

Lugol solution is often administered to patients with Graves' disease before surgery. The aim is to reduce thyroid vascularization and surgical morbidity, but its real effectiveness remains controversial. The present study was designed to evaluate the effects of preoperative Lugol solution on thyroid vascularization and surgical morbidity in patients with Graves' disease undergoing total thyroidectomy.

Methods

Fifty-six patients undergoing total thyroidectomy for Graves' disease were randomly assigned to receive 7 days of Lugol treatment (Lugol+ group, 29) or no Lugol treatment (LS- group, 27) before surgery in this single-centre and single-blinded trial. Preoperative hormone and colour Doppler ultrasonographic data for assessing thyroid vascularization were colle

SUBMITTER: Schiavone D 

PROVIDER: S-EPMC11977759 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature