Markers of neutrophil activation and some immune and haematological indices in malaria infection during pregnancy.

ABSTRACT:

Background

Neutrophils are the first responders to pathogen invasion and are important first-line defenders. The defence mechanism of activated neutrophils includes neutrophil extracellular traps (NETs) formation that immobilize pathogens, stop their spread within the tissues, and ultimately kill them. However, their roles in the context of malaria during pregnancy are still elusive. This study was conducted to investigate markers of neutrophil activation as well as immunological and haematological cellular responses during Plasmodium infection in pregnancy.

Method

A total of 340 pregnant women aged between 19 and 42 years were recruited for this study carried out in South-east, Nigeria. All the subjects were tested for malaria parasite (MP) status. Those infected with human

SUBMITTER: Chukwuanukwu RC 

PROVIDER: S-EPMC11978171 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature