Molecular interaction study of L-Ornithine with bovine serum albumin using spectroscopic and molecular docking methods.

ABSTRACT: Activates the pituitary gland, leading to increased secretion of growth hormone. This activation plays a crucial role in growth, metabolism, and tissue repair. Bovine serum albumin, a well-studied protein, demonstrates the interaction between proteins-ligands and transports various compounds in the bloodstream. This study elucidates the molecular interactions between L-ornithine and BSA through spectroscopic analysis, identifying binding modes, constants, and structural changes. Molecular docking techniques are employed to correlate with experimental data from fluorescence and UV spectroscopy analyses.The study uses Fourier transform infrared spectroscopy, UV-Visible spectroscopy, fluorescence spectroscopy, circular dichroism spectroscopy and molecular docking to analyze the interaction be

SUBMITTER: Koundal S 

PROVIDER: S-EPMC11978791 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature