Ocular manifestations of Juvenile Systemic Lupus Erythematosus: a systematic review.

ABSTRACT: Juvenile-onset Systemic Lupus Erythematosus (JSLE) is a chronic multifactorial autoimmune disease with multiple system involvement, affecting children and adolescents. Ocular manifestations are rare and can range from mild to severe. JSLE impacts quality of life and prognosis. However, the impact JSLE has on children's ocular health remains an underexplored area. This systematic review aims to consolidate existing evidence on ocular manifestations in JSLE. A systematic search of MEDLINE and ScienceDirect was conducted until October 2024. Eligible studies focused on children and adolescents with JSLE presenting ocular symptoms. Joanna Briggs Institute critical appraisal tools for each study were employed for quality assessment. Forty-two studies evaluating ocular manifestations in JSLE pati

SUBMITTER: Nikolaidou A 

PROVIDER: S-EPMC11978895 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature