Pathogenicity and host-interacting mechanisms of enterogenic <i>Enterobacter cancerogenus</i> in silkworm.

ABSTRACT:

Introduction

Enterobacter cancerogenus (E. cancerogenus) is a facultative anaerobic, gram-negative bacterium that can be utilized for the biological control of pests. However, the molecular mechanisms underlying the pathogenicity of E. cancerogenus in insect hosts remain largely unexplored.

Methods

In this study, the Bombyx mori model was employed to investigate the pathogenicity of E. cancerogenus strain ECL7, a bacterium pathogenic to silkworms, through whole-genome sequencing, 16S rDNA sequencing, and transcriptome analysis.

Results

The results revealed that ECL7 harbors virulence genes associated with biofilm formation, adhesion, type III secretion system (T3SS), type VI secretion system (T6SS), and other factors, which collectively lea

SUBMITTER: Luo M 

PROVIDER: S-EPMC11979111 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature