Whole-genome-based characterization of <i>Escherichia albertii</i> strains isolated from paediatric diarrhoeal cases in Kolkata, India.

ABSTRACT: Escherichia albertii is a Gram-negative facultative anaerobic bacterium that causes diarrhoea in humans. This study shows the isolation of E. albertii from hospitalized paediatric diarrhoeal cases and genome-based characteristics with putative virulence factors and antimicrobial resistance. E. albertii isolates were identified by species-specific PCR, targeting the gene encoding cytolethal distending toxin (Ea-cdt). The genome of E. albertii was sequenced to identify (i) genes encoding virulence factors (ii) antibiotic resistance-encoding genes, including the mobile genetic elements and (iii) core gene-based phylogenetic relationships and pan-genome features. A total of 10 (1.2%) E. albertii isolates were isolated from 854 faecal samples, of which

SUBMITTER: Chowdhury G 

PROVIDER: S-EPMC11979293 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature