Diagnostic value of bone scintigraphy versus cardiovascular magnetic resonance in cardiac amyloidosis.

ABSTRACT:

Background

Accurate diagnosis of transthyretin amyloidosis cardiomyopathy (ATTR-CM) and its differentiation from light-chain (AL) cardiac amyloidosis (CA) cases (AL-CM) are of paramount importance. Surprisingly, comparative imaging data based on concurrent cardiovascular magnetic resonance (CMR) and bone scintigraphy in the same patients with biopsy-proven diagnosis of CA are still rare.

Methods

This was a real-world retrospective single-center study based on a local clinical care pipeline and we carefully analyzed clinical, laboratory, CMR, and bone scintigraphy data (and if necessary additional endomyocardial biopsy [EMB] data) in patients with suspected CA. As a major inclusion criterion, we only looked at those patients who underwent both a CMR study and a bone scintigra

SUBMITTER: Obergassel J 

PROVIDER: S-EPMC11979466 | biostudies-literature | 2025 Summer

REPOSITORIES: biostudies-literature