Comparison of available methods to evaluate cefiderocol susceptibility in Acinetobacter spp.

ABSTRACT: Recently, considerable uncertainty has arisen concerning the appropriate susceptibility testing for cefiderocol in gram-negative bacilli, particularly in the context of its application to Acinetobacter spp. The optimal method for assessing the susceptibility levels of Acinetobacter spp. to cefiderocol remains a subject of debate due to substantial disparities observed in the values obtained through various testing procedures. This study employed four minimum inhibitory concentration (MIC) methodologies and the disk diffusion to assess the susceptibility of twenty-seven carbapenem resistant (CR)-Acinetobacter strains to cefiderocol. The results from our study reveal significant variations in the minimum inhibitory concentration (MIC) values obtained with the different methods and in the lev

SUBMITTER: Pasteran F 

PROVIDER: S-EPMC11979972 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature