Efficacy of repeat hepatectomy versus radiofrequency ablation for recurrent hepatocellular carcinoma: a Systematic Review and meta-analysis.

ABSTRACT:

Background

This article compared the efficacy and safety of repeat hepatectomy (RH) and radiofrequency ablation (RFA) for the treatment of recurrent hepatocellular carcinoma (RHCC) from multiple perspectives.

Methods

We systematically searched PubMed, Embase, Web of Science, and CNKI from January 2008 to December 2023. We collected all relevant articles and assessed the quality of the data. We analyzed the data for the primary outcomes of overall survival (OS) and disease-free survival (DFS), and secondary outcomes of postoperative complications, recurrence rate, and survival benefit. Subgroup analyses were performed for tumor diameter, patient origin, and publication date.

Results

A total of 38 studies were included, comprising 5,339 patients. OS was similar in both

SUBMITTER: Meng Q 

PROVIDER: S-EPMC11979987 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature