Platelet-rich plasma with versus without hyaluronic acid for hip osteoarthritis: a systematic review and meta-analysis.

ABSTRACT:

Background

The use of intra-articular orthobiologics in hip osteoarthritis (HOA) has been presented as a therapeutic option and to postpone arthroplasty. There is little scientific evidence on the clinical application of platelet-rich plasma (PRP) associated with hyaluronic acid as dual therapy. Thus, the aim of our systematic review is to compare the clinical improvement with the use of PRP with versus without hyaluronic acid (HA) in hip osteoarthritis.

Methods

We systematically searched Cochrane, PubMed, and Embase databases for studies evaluating patients with HOA who received PRP with vs. without HA. Pain and functional score were collected and pooled at 3-, 6-, and 12-months follow-up. Mean differences (MD) and 95% intervals were calculated, and heterogeneity was assess

SUBMITTER: Santiago MS 

PROVIDER: S-EPMC11980421 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature