Risk Score Predicting Primary Open-Angle Glaucoma Patients With Vascular Predisposition.

ABSTRACT:

Purpose

We tested the hypothesis that a questionnaire-based risk score predicts the prevalence of patients with primary open-angle glaucoma (POAG) with vascular predisposition.

Methods

The Flammer Syndrome Questionnaire (FSQ) was used to determine vascular risk scores in 823 healthy subjects and 512 patients with POAG. Next, we characterized blood flow pulsatility changes within the optic nerve head (ONH) in Flammer syndrome (FS) using laser speckle flowgraphy (LSFG) in 358 eyes of 206 patients with normal-tension glaucoma (NTG). Last, we examined the association between changes in Mean blur rate (MBRAve), an LSFG-derived ONH blood flow measurement, during cold provocation and the FSQ risk score in 56 eyes of 56 patients with NTG.

Results

Five FSQ-related symptoms wer

SUBMITTER: Takahashi N 

PROVIDER: S-EPMC11980953 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature