Exploring the content validity of the EQ-5D-5L and four bolt-ons (skin irritation, self-confidence, sleep, social relationships) in atopic dermatitis and chronic urticaria.

ABSTRACT:

Background

The objective of this study was to assess the content validity of the EQ-5D-5L and four bolt-ons: skin irritation, self-confidence, social relationships and sleep, for people with atopic dermatitis (AD) and chronic urticaria (CU).

Methods

Adults with AD or CU in the United Kingdom, with varying levels of severity, participated in either online or in-person semi-structured interviews. During the interviews, participants were first asked about the symptoms and impacts of their condition. They were then asked to complete the EQ-5D-5L and four bolt-ons using 'think-aloud' and retrospective probing. Interviews were recorded, transcribed, then analysed using content and thematic analysis.

Results

Thirty participants (N = 15 with AD; N = 15 with CU) were interview

SUBMITTER: Sussex AK 

PROVIDER: S-EPMC11982113 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature