Establishment and validation survival prediction models for T1 locally advanced breast cancer after breast conservation surgery versus mastectomy.

ABSTRACT: Previous reports have indicated that the survival rate of total mastectomy (TM) is higher than that of breast-conserving surgery (BCS). This study established survival prediction models for T1-stage locally advanced breast cancer (LABC) comparing TM and BCS, aiming to identify risk factors for overall survival (OS) associated with different surgical approaches and provide a basis for individualized treatment by clinicians. Cases of pathologically confirmed T1 LABC between 2010 and 2015 were retrieved from the Surveillance Epidemiology and End Results (SEER) database. COX regression analysis was used to analyze the relationship between LABC TM, BCS and various factors. Hazard ratio (HR) and 95% confidence interval (95%CI) were calculated to determine the possible influencing factors. Signif

SUBMITTER: Qian F 

PROVIDER: S-EPMC11982249 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature