ER stress and viral defense: Advances and future perspectives on plant unfolded protein response in pathogenesis.

ABSTRACT: Viral infections pose significant threats to crop productivity and agricultural sustainability. The frequency and severity of these infections are increasing, and pathogens are evolving rapidly under the influence of climate change. This underscores the importance of exploring the fundamental mechanisms by which plants defend themselves against dynamic viral threats. One such mechanism is the unfolded protein response (UPR), which is activated when the protein folding demand exceeds the capacity of the endoplasmic reticulum, particularly under adverse environmental conditions. While the key regulators of the UPR in response to viral infections have been identified, our understanding of how they modulate the UPR to suppress plant viral infections at the molecular and genetic levels is still

SUBMITTER: Adhikari B 

PROVIDER: S-EPMC11982459 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature