Association Between Helicobacter Pylori Infection and Periodontal and Gastric Diseases: A Meta-Analysis.

ABSTRACT:

Background

Helicobacter pylori (Hp) infection has been implicated in both gastric and extra-gastric diseases, including periodontitis.

Methods

This meta-analysis investigated the association between Helicobacter pylori (Hp) infection and periodontitis by systematically reviewing eight studies. The analysis was conducted using the R package "meta," employing both fixed effects and random effects models. The level of heterogeneity among the studies was assessed using the I-squared statistic and tau values. Publication bias was evaluated through funnel plots, Begg's rank correlation, and Egger's regression tests to ensure the robustness of the findings.

Results

The meta-analysis included a total of 6061 observations, with 1404 cases of periodontitis. The fixed effects mo

SUBMITTER: Liu Q 

PROVIDER: S-EPMC11982461 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature