Cherenkov Imaged Bio-Morphological Features Verify Patient Positioning With Deformable Tissue Translocation in Breast Radiation Therapy.

ABSTRACT:

Purpose

Accurate patient positioning is crucial for precise radiation therapy dose delivery, as errors in positioning can profoundly influence treatment outcomes. This study introduces a novel application for loco-regional tissue deformation tracking via Cherenkov image analysis during fractionated breast cancer radiation therapy. The primary objective of this research was to develop and test an algorithmic method for Cherenkov-based position accuracy quantification, particularly for loco-regional deformations, which do not have an ideal method for quantification during radiation therapy.

Methods and materials

Bio-morphological features in the Cherenkov images, such as vessels, were segmented. A rigid/nonrigid combined registration technique was employed to pinpoint both int

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11982963 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature