Single Enema Fecal Microbiota Transplantation in Cats With Chronic Enteropathy.

ABSTRACT:

Background

Chronic enteropathies (CE) are common in cats, and alterations of the intestinal microbiota might be involved in the pathogenesis.

Hypothesis/objectives

To evaluate the efficacy of a single enema fecal microbiota transplantation (FMT) in improving intestinal dysbiosis and clinical scores in cats with CE.

Animals

Twenty-eight cats with either chronic inflammatory enteropathy (CIE; n = 19) or small cell gastrointestinal lymphoma (SCGL; n = 9) were prospectively enrolled.

Methods

Eleven cats were randomly selected to receive a single enema FMT (FMT-group), and 17 cats were used as controls. Clinical activity was determined using the Feline Chronic Enteropathy Activity Index (FCEAI), and intestinal dysbiosis was determined using the feline dysbiosis inde

SUBMITTER: Karra DA 

PROVIDER: S-EPMC11983779 | biostudies-literature | 2025 May-Jun

REPOSITORIES: biostudies-literature