Maximizing horizontal transmission through mating: increased mating frequency and mating competitiveness associated with Microsporidia MB-infected Anopheles arabiensis males.

ABSTRACT:

Background

Microsporidia MB is a naturally occurring symbiont in Anopheles arabiensis mosquitoes that inhibits the development of Plasmodium. It is transmitted both vertically and horizontally, enabling its spread within mosquito populations. Currently, mating is the only known mechanism for horizontal transmission. Understanding the factors that influence Microsporidia MB transmission during mating is crucial for developing a malaria transmission-blocking strategy based on this symbiont.

Methods

The effect of mosquito age on Microsporidia MB transmission was determined through mating bioassays between infected and uninfected Anopheles arabiensis males and females in three age groups: 3-4 days, 7-8 days, and 10-11 days. Mating bioassays were also conducted to determine if Mi

SUBMITTER: Maina T 

PROVIDER: S-EPMC11983955 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature