The fasting plasma glucose to high-density lipoprotein cholesterol ratio: a novel index for identifying NAFLD.

ABSTRACT:

Background

Previous research has indicated that the fasting plasma glucose to high-density lipoprotein cholesterol ratio (FHR) is a novel biomarker for assessing cardiovascular disease prognosis. The objective of this study is to investigate the potential relationship of FHR with non-alcoholic fatty liver disease (NAFLD).

Methods

The present study employed a retrospective design and included 14,251 participants who underwent health examinations. Restricted cubic spline regression and multivariable logistic regression were used to assess the relationship of NAFLD with FHR. The performance of the FHR in identifying NAFLD was analyzed through receiver operating curve analysis.

Results

After adjustment for confounders, a positive association of FHR with NAFLD was observed

SUBMITTER: Yu C 

PROVIDER: S-EPMC11984220 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature