Novel brain biomarkers of obesity in young adult women based on statistical measurements of white matter tracts.

ABSTRACT:

Objective

Novel brain biomarkers of obesity were sought by studying statistical measurements on fractional anisotropy (FA) images of different white matter (WM) tracts from young adult women.

Methods

Tract measurements were chosen that showed differences between two groups (normal weight and overweight/obese) and that were correlated with BMI. From these measurements, a simple and novel process was applied to select those that would allow the creation of models to quantify and classify the state of obesity of individuals. The biomarkers were created from the tract measurements used in the models.

Results

Positive correlations were found between WM integrity and BMI, mainly in tracts involved in motor functions. From these results, two models were built to quantify and

SUBMITTER: Suarez-Garcia JG 

PROVIDER: S-EPMC11984704 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature