Characterization of metabolic features derived from the non-polar metabolite UHPLC-QTOF dataset of <i>Jaspis sp.</i> Collected from the waters off Pulau Banggi, Sabah, Malaysia.

ABSTRACT: The marine biome is a rich source of bioactive compounds. The discovery of anti-cancer compounds in Cryptotheca crypta in 1950 initiated a wave of bioprospecting efforts focused on marine sponges. Jaspis sp., a marine sponge, has been reported to exhibit anti-cancer activity against human colorectal cancer. A sample of Jaspis sp., collected from the waters off Pulau Banggi, Sabah, Malaysia, was analyzed through a non-polar metabolite survey. The non-polar crude extract was profiled using UHPLC-QTOF in both positive and negative modes. The detected metabolic features were clustered, and representative features were tentatively identified through a combination of spectral database searches (using various MS2 spectral databases) and in silico compound identificatio

SUBMITTER: Lee DJH 

PROVIDER: S-EPMC11985046 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature