Heterogeneous Visual Function Deficits in Intermediate Age-Related Macular Degeneration: A MACUSTAR Report.

ABSTRACT:

Objective

To examine the extent to which visual function in Beckman age-related macular degeneration (AMD) disease stages differs from age-similar peers with no AMD and, using reference limits derived from those with no AMD, test the hypothesis that people with intermediate AMD (iAMD) have heterogeneous visual function deficits.

Design

Cross-sectional analyses of a range of baseline visual function measures from the MACUSTAR study-an international, multicenter (n = 20), noninterventional clinical trial.

Participants

Five hundred eighty-five participants with iAMD (67% female, mean [standard deviation] age 72 [7] years) were recruited alongside 56 with no AMD (59% female, 68 [6]), 34 with early AMD (79% female, 72 [6]), and 43 with late AMD (49% female, 75 [6]).

Met

SUBMITTER: Dunbar HMP 

PROVIDER: S-EPMC11985047 | biostudies-literature | 2025 Jul-Aug

REPOSITORIES: biostudies-literature